The collection is comprised of papers from Dr. I. Henderson Lutterloh and his son Dr. I. Hayden Lutterloh. It includes correspondence, licenses and receipts from Lutterloh Clinic and Drugstore, medical informational booklets, and handwritten notes from Hayden's education at Jefferson Medical College. Also included is a book based on Hayden's recollections of medicine in Sanford beginning with his father.